Journal of Vascular and Interventional Radiology
Volume 13, Issue 9, Part 1 , Pages 883-886, September 2002

Prospective Evaluation of Pain Relief in 100 Patients Undergoing Percutaneous Vertebroplasty: Results and Follow-up

  • J. Kevin McGraw, MD

      Affiliations

    • Corresponding Author InformationAddress correspondence to J.K.M., Department of Vascular and Interventional Radiology, Riverside Methodist Hospital, 3555 Olentangy River Rd., Suite 2050, Columbus, OH 43214
    • Department of Vascular and Interventional Radiology, Riverside Methodist Hospital, Columbus
    • ,
  • John A. Lippert, MD

      Affiliations

    • Department of Vascular and Interventional Radiology, Riverside Methodist Hospital, Columbus
    • ,
  • Kirk D. Minkus, MD

      Affiliations

    • Department of Interventional Radiology, St. Vincent Mercy Medical Center, Toledo, Ohio
    • ,
  • Parag M. Rami, MD

      Affiliations

    • Department of Interventional Radiology, St. Vincent Mercy Medical Center, Toledo, Ohio
    • ,
  • Thomas M. Davis, MD

      Affiliations

    • Department of Vascular and Interventional Radiology, Riverside Methodist Hospital, Columbus
    • ,
  • Ronald F. Budzik, MD

      Affiliations

    • Department of Vascular and Interventional Radiology, Riverside Methodist Hospital, Columbus

Received 27 February 2002; received in revised form 10 April 2002 and 22 May 2002; accepted 22 May 2002.

PURPOSE

To determine the efficacy and durability of percutaneous vertebroplasty for the treatment of back pain associated with vertebral body compression fractures.

MATERIALS AND METHODS

One hundred patients (79 women, 21 men; mean age, 73.7 y) underwent 156 percutaneous injections of polymethylmethacrylate (PMMA) into a vertebra (68 thoracic and 88 lumbar) under fluoroscopic guidance over a 35-month period. Before the procedure and at follow-up, patients were asked to quantify their pain on a visual analog scale (VAS) and complete a follow-up questionnaire of our own design.

RESULTS

The procedure was technically successful in all patients. There were two complications. One patient sustained a sternal fracture and one experienced a transient radiculopathy. Ninety-seven patients (97%) reported significant pain relief 24 hours after treatment. Mean follow-up duration was 21.5 months (6–44 mo) in 99 patients. Ninety-two patients (93%) reported significant improvement in back pain previously associated with their compression fractures as well as improved ambulatory ability. Before vertebroplasty, the VAS score for the 99 patients was 8.91 ± 1.12 compared to a score of 2.02 ± 1.95 at follow-up. The mean difference in VAS scores was significant (P < .0001).

CONCLUSION

Percutaneous vertebroplasty of symptomatic vertebral body compression fractures is a minimally invasive procedure that provides immediate and sustained pain relief in patients with refractory pain.

Index terms:  Pain , Spine, fractures , Vertebroplasty

Abbreviations:  PMMA, polymethylmethacrylate , VAS, visual analog scale

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 None of the authors has identified a conflict of interest.

PII: S1051-0443(07)61770-9

doi:10.1016/S1051-0443(07)61770-9

Journal of Vascular and Interventional Radiology
Volume 13, Issue 9, Part 1 , Pages 883-886, September 2002

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