Journal of Vascular and Interventional Radiology
Volume 19, Issue 3 , Pages 309-318, March 2008

N-Acetylcysteine Use to Prevent Contrast Medium–induced Nephropathy: Premature Phase III Trials

  • David A. Stenstrom

      Affiliations

    • Department of Neurology, Oregon Health & Science University, Portland, Oregon
  • ,
  • Leslie L. Muldoon, PhD

      Affiliations

    • Department of Neurology, Oregon Health & Science University, Portland, Oregon
    • Department of Cell and Developmental Biology, Oregon Health & Science University, Portland, Oregon
  • ,
  • Hector Armijo-Medina, MD

      Affiliations

    • Department of Neurology, Oregon Health & Science University, Portland, Oregon
  • ,
  • Suzanne Watnick

      Affiliations

    • Division of Hospital and Specialty Medicine, Nephrology Section, Portland, Oregon
  • ,
  • Nancy D. Doolittle, PhD

      Affiliations

    • Department of Neurology, Oregon Health & Science University, Portland, Oregon
  • ,
  • John A. Kaufman, MD

      Affiliations

    • Department of Angiography, Oregon Health & Science University, Portland, Oregon
  • ,
  • Darryl R. Peterson, PhD

      Affiliations

    • Department of Physiology and Biophysics, Rosalind Franklin University of Medicine and Science, The Chicago Medical School, North Chicago, Illinois.
  • ,
  • Joseph Bubalo, PharmD

      Affiliations

    • Pharmacy Department, Oregon Health & Science University, Portland, Oregon
  • ,
  • Edward A. Neuwelt, MD

      Affiliations

    • Department of Neurology, Oregon Health & Science University, Portland, Oregon
    • Department of Neurosurgery, Oregon Health & Science University, Portland, Oregon
    • Portland Veterans Administration Medical Center, Portland, Oregon
    • Corresponding Author InformationAddress correspondence to E.A.N., Department of Neurology, Oregon Health & Science University, 3181 SW Sam Jackson Parkway, L603, Portland, OR 97239

Received 16 August 2007; received in revised form 31 October 2007; accepted 1 November 2007.

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 E.A.N., L.L.M., Oregon Health & Science University, Portland Veterans Affairs Medical Center, and the Department of Veterans Affairs have significant financial interest in Adherex (Durham, NC), a company that may have a commercial interest in the results of this research and technology. This potential conflict of interest was reviewed and managed by the Oregon Health & Science University Integrity Program Oversight Council and the Portland Veterans Affairs Medical Center Conflict of Interest in Research Committee. E.A.N. has divested his financial interests in Adherex. This work was supported by a Veterans Administration Merit Review Grant and by National Institutes of Health grants NS33618 and NS44687 from the National Institute of Neurological Disorders and Stroke to E.A.N.

PII: S1051-0443(07)01434-0

doi:10.1016/j.jvir.2007.11.003

Journal of Vascular and Interventional Radiology
Volume 19, Issue 3 , Pages 309-318, March 2008