Journal of Vascular and Interventional Radiology
Volume 19, Issue 11 , Pages 1576-1581 , November 2008

Factors Predicting Survival after Transjugular Intrahepatic Portosystemic Shunt Creation: 15 Years' Experience from a Single Tertiary Medical Center

  • Jen-Jung Pan, MD, PhD

      Affiliations

    • Division of Gastroenterology, Hepatology and Nutrition, Department of Medicine, University of Florida, 1600 Southwest Archer Road, Room M-440, Gainesville, FL 32610
    • ,
  • Chaoru Chen, PhD

      Affiliations

    • Division of Gastroenterology, Hepatology and Nutrition, Department of Medicine, University of Florida, 1600 Southwest Archer Road, Room M-440, Gainesville, FL 32610
    • ,
  • James G. Caridi, MD

      Affiliations

    • Department of Radiology, University of Florida, 1600 Southwest Archer Road, Room M-440, Gainesville, FL 32610
    • ,
  • Brian Geller, MD

      Affiliations

    • Department of Radiology, University of Florida, 1600 Southwest Archer Road, Room M-440, Gainesville, FL 32610
    • ,
  • Roberto Firpi, MD

      Affiliations

    • Division of Gastroenterology, Hepatology and Nutrition, Department of Medicine, University of Florida, 1600 Southwest Archer Road, Room M-440, Gainesville, FL 32610
    • ,
  • Victor I. Machicao, MD

      Affiliations

    • Division of Gastroenterology, Hepatology and Nutrition, Department of Medicine, University of Florida, 1600 Southwest Archer Road, Room M-440, Gainesville, FL 32610
    • ,
  • Irvin F. Hawkins Jr, MD

      Affiliations

    • Department of Radiology, University of Florida, 1600 Southwest Archer Road, Room M-440, Gainesville, FL 32610
    • ,
  • Consuelo Soldevila-Pico, MD

      Affiliations

    • Division of Gastroenterology, Hepatology and Nutrition, Department of Medicine, University of Florida, 1600 Southwest Archer Road, Room M-440, Gainesville, FL 32610
    • ,
  • David R. Nelson, MD

      Affiliations

    • Division of Gastroenterology, Hepatology and Nutrition, Department of Medicine, University of Florida, 1600 Southwest Archer Road, Room M-440, Gainesville, FL 32610
    • ,
  • Giuseppe Morelli, MD

      Affiliations

    • Division of Gastroenterology, Hepatology and Nutrition, Department of Medicine, University of Florida, 1600 Southwest Archer Road, Room M-440, Gainesville, FL 32610
    • Corresponding Author InformationAddress correspondence to G.M.

Received 12 November 2007 ,Revised 15 July 2008 ,Accepted 21 July 2008.

References 

  1. Coldwell DM, Ring EJ, Rees CR, et al. Multicenter investigation of the role of transjugular intrahepatic portosystemic shunt in management of portal hypertension. Radiology. 1995;196:335–340
  2. Papatheodoridis GV, Goulis J, Leandro G, et al. Transjugular intrahepatic portosystemic shunt compared with endoscopic treatment for prevention of variceal rebleeding: a meta-analysis. Hepatology. 1999;30:612–622
  3. Luca A, D'Amico G, La Galla R, et al. TIPS for prevention of recurrent bleeding in patients with cirrhosis: meta-analysis of randomized clinical trials. Radiology. 1999;212:411–421
  4. Ferguson JW, Hayes PC. Transjugular intrahepatic portosystemic shunt in the prevention of rebleeding in oesophageal varices. Eur J Gastroenterol Hepatol. 2006;18:1167–1171
  5. McAvoy NC, Hayes PC. The use of transjugular intrahepatic portosystemic stent shunt in the management of acute oesophageal variceal haemorrhage. Eur J Gastroenterol Hepatol. 2006;18:1135–1141
  6. Saravanan R, Nayar M, Gilmore IT, et al. Transjugular intrahepatic portosystemic stent shunt: 11 years' experience at a regional referral centre. Eur J Gastroenterol Hepatol. 2005;17:1165–1171
  7. Lebrec D, Giuily N, Hadengue A, et al. Transjugular intrahepatic portosystemic shunts: comparison with paracentesis in patients with cirrhosis and refractory ascites: a randomized trial (French Group of Clinicians and a Group of Biologists). J Hepatol. 1996;25:135–144
  8. Rossle M, Ochs A, Gulberg V, et al. A comparison of paracentesis and transjugular intrahepatic portosystemic shunting in patients with ascites. N Engl J Med. 2000;342:1701–1702
  9. Gines P, Uriz J, Calahorra B, et al. Transjugular intrahepatic portosystemic shunting versus paracentesis plus albumin for refractory ascites in cirrhosis. Gastroenterology. 2002;123:1839–1847
  10. Sanyal AJ, Genning C, Reddy KR, et al. The North American Study for the Treatment of Refractory Ascites. Gastroenterology. 2003;124:634–641
  11. Salerno F, Merli M, Riggio O, et al. Randomized controlled study of TIPS versus paracentesis plus albumin in cirrhosis with severe ascites. Hepatology. 2004;40:629–635
  12. D'Amico G, Luca A, Morabito A, et al. Uncovered transjugular intrahepatic portosystemic shunt for refractory ascites: a meta-analysis. Gastroenterology. 2005;129:1282–1293
  13. Silva RF, Arroyo PCJ, Duca WJ, et al. Complications following transjugular intrahepatic portosystemic shunt: a retrospective analysis. Transplant Proc. 2004;36:926–928
  14. Freedman AM, Sanyal AJ, Tisnado J, et al. Complications of transjugular intrahepatic portosystemic shunt: a comprehensive review. Radiographics. 1993;13:1185–1210
  15. Boyer TD, Haskal ZJ. American Association for the Study of Liver Diseases Practice Guidelines: the role of transjugular intrahepatic portosystemic shunt creation in the management of portal hypertension. J Vasc Interv Radiol. 2005;16:615–629
  16. Nazarian GK, Bjarnason H, Dietz CA, et al. Refractory ascites: midterm results of treatment with a transjugular intrahepatic portosystemic shunt. Radiology. 1997;205:173–180
  17. Chalasani N, Clark WS, Martin LG, et al. Determinants of mortality in patients with advanced cirrhosis after transjugular intrahepatic portosystemic shunting. Gastroenterology. 2000;118:138–144
  18. Rajan DK, Haskal ZJ, Clark TW. Serum bilirubin and early mortality after transjugular intrahepatic portosystemic shunts: results of a multivariate analysis. J Vasc Interv Radiol. 2002;13:155–161
  19. Russo MW, Jacques PF, Mauro M, et al. Predictors of mortality and stenosis after transjugular intrahepatic portosystemic shunt. Liver Transpl. 2002;8:271–277
  20. Yoon CJ, Chung JW, Park JH. Transjugular intrahepatic portosystemic shunt for acute variceal bleeding in patients with viral liver cirrhosis: predictors of early mortality. AJR Am J Roentgenol. 2005;185:885–889
  21. Gerbes AL, Gulberg V. Benefit of TIPS for patients with refractory or recidivant ascites: serum bilirubin may make the difference. Hepatology. 2005;41:217
  22. Membreno F, Baez AL, Pandula R, et al. Differences in long-term survival after transjugular intrahepatic portosystemic shunt for refractory ascites and variceal bleed. J Gastroenterol Hepatol. 2005;20:474–481
  23. Malinchoc M, Kamath PS, Gordon FD, et al. A model to predict poor survival in patients undergoing transjugular intrahepatic portosystemic shunts. Hepatology. 2000;31:864–871
  24. Ferral H, Gamboa P, Postoak DW, et al. Survival after elective transjugular intrahepatic portosystemic shunt creation: prediction with model for end-stage liver disease score. Radiology. 2004;231:231–236
  25. Montgomery A, Ferral H, Vasan R, et al. MELD score as a predictor of early death in patients undergoing elective transjugular intrahepatic portosystemic shunt (TIPS) procedures. Cardiovasc Intervent Radiol. 2005;28:307–312
  26. Harrod-Kim P, Saad W, Waldman D. Predictors of early mortality after transjugular intrahepatic portosystemic shunt creation for the treatment of refractory ascites. J Vasc Interv Radiol. 2006;17:1605–1610
  27. Kamath PS, Wiesner RH, Malinchoc M, et al. A model to predict survival in patients with end-stage liver disease. Hepatology. 2001;33:464–470

 None of the authors have identified a conflict of interest.

PII: S1051-0443(08)00678-7

doi: 10.1016/j.jvir.2008.07.021

Journal of Vascular and Interventional Radiology
Volume 19, Issue 11 , Pages 1576-1581 , November 2008

Article Tools

* Image Usage & Resolution