Pulmonary Edema as a Complication of Transcatheter Embolization of Renal Angiomyolipoma in a Patient with Pulmonary Lymphangioleiomyomatosis Due to Tuberous Sclerosis Complex

Hiraki, Takao; Mimura, Hidefumi; Gobara, Hideo; Fujiwara, Hiroyasu; Iguchi, Toshihiro; Sakurai, Jun; Norikane, Seiichiro; Kato, Katsuya; Kanazawa, Susumu

doi:10.1016/j.jvir.2009.02.019

« Previous Next »Journal of Vascular and Interventional Radiology
Volume 20, Issue 6 , Pages 819-823, June 2009

Pulmonary Edema as a Complication of Transcatheter Embolization of Renal Angiomyolipoma in a Patient with Pulmonary Lymphangioleiomyomatosis Due to Tuberous Sclerosis Complex

Takao Hiraki, MD
- Department of Radiology, Okayama University Medical School, 2-5-1 Shikatacho, Okayama 700-8558, Japan
- Address correspondence to T.H.
Hidefumi Mimura, MD
- Department of Radiology, Okayama University Medical School, 2-5-1 Shikatacho, Okayama 700-8558, Japan
Hideo Gobara, MD
- Department of Radiology, Okayama University Medical School, 2-5-1 Shikatacho, Okayama 700-8558, Japan
Hiroyasu Fujiwara, MD
- Department of Radiology, Okayama University Medical School, 2-5-1 Shikatacho, Okayama 700-8558, Japan
Toshihiro Iguchi, MD
- Department of Radiology, Fukuyama City Hospital, Fukuyama, Japan
Jun Sakurai, MD
- Department of Radiology, Okayama University Medical School, 2-5-1 Shikatacho, Okayama 700-8558, Japan
Seiichiro Norikane, MD
- Department of Radiology, Okayama University Medical School, 2-5-1 Shikatacho, Okayama 700-8558, Japan
Katsuya Kato, MD
- Department of Radiology, Okayama University Medical School, 2-5-1 Shikatacho, Okayama 700-8558, Japan
Susumu Kanazawa, MD
- Department of Radiology, Okayama University Medical School, 2-5-1 Shikatacho, Okayama 700-8558, Japan

Received 25 March 2008; received in revised form 17 February 2009; accepted 19 February 2009.

Tuberous sclerosis complex (TSC) is an autosomal-dominant disorder characterized by seizures, mental retardation, and various hamartomatous lesions, including renal angiomyolipoma (AML) and pulmonary lymphangioleiomyomatosis. A 22-year-old woman with TSC presented with multiple renal AMLs exceeding 4 cm in diameter. She underwent two transcatheter embolization procedures with a mixture of ethanol and iodized oil. She complained of dyspnea and minor hemoptysis 4 and 6 hours after the procedure. Findings on chest radiographs and computed tomographic images were indicative of pulmonary edema. The patient was treated with conservative therapy. The possible causes of the pulmonary edema are discussed in the text.

Abbreviations: AML, angiomyolipoma, LAM, lymphangioleiomyomatosis, TSC, tuberous sclerosis complex