Journal of Vascular and Interventional Radiology
Volume 20, Issue 9 , Pages 1224-1229 , September 2009

Microwave Ablation versus Radiofrequency Ablation in the Kidney: High-power Triaxial Antennas Create Larger Ablation Zones than Similarly Sized Internally Cooled Electrodes

  • Paul F. Laeseke, MD, PhD

      Affiliations

    • Department of Radiology, University of Wisconsin, 600 Highland Avenue, Madison, WI 53792
    • Corresponding Author InformationAddress correspondence to P.F.L.
  • ,
  • Fred T. Lee Jr, MD

      Affiliations

    • Department of Radiology, University of Wisconsin, 600 Highland Avenue, Madison, WI 53792
  • ,
  • Lisa A. Sampson, BS, CVT

      Affiliations

    • Department of Radiology, University of Wisconsin, 600 Highland Avenue, Madison, WI 53792
  • ,
  • Daniel W. van der Weide, PhD

      Affiliations

    • Department of Electrical and Computer Engineering, University of Wisconsin, 600 Highland Avenue, Madison, WI 53792
  • ,
  • Christopher L. Brace, PhD

      Affiliations

    • Department of Radiology, University of Wisconsin, 600 Highland Avenue, Madison, WI 53792

Received 1 October 2008 ,Revised 12 May 2009 ,Accepted 15 May 2009.

References 

  1. Lipworth L, Tarone RE, McLaughlin JK. The epidemiology of renal cell carcinoma. J Urol. 2006;176:2353–2358
  2. Chow WH, Devesa SS, Warren JL, Fraumeni JF. Rising incidence of renal cell cancer in the United States. JAMA. 1999;281:1628–1631
  3. Leslie JA, Prihoda T, Thompson IM. Serendipitous renal cell carcinoma in the post-CT era: continued evidence in improved outcomes. Urol Oncol. 2003;21:39–44
  4. Hwang JJ, Walther MM, Pautler SE, et al. Radio frequency ablation of small renal tumors: intermediate results. J Urol. 2004;171:1814–1818
  5. Gervais DA, McGovern FJ, Arellano RS, McDougal WS, Mueller PR. Radiofrequency ablation of renal cell carcinoma: part 1, indications, results, and role in patient management over a 6-year period and ablation of 100 tumors. AJR Am J Roentgenol. 2005;185:64–71
  6. Zagoria RJ, Traver MA, Werle DM, Perini M, Hayasaka S, Clark PE. Oncologic efficacy of CT-guided percutaneous radiofrequency ablation of renal cell carcinomas. AJR Am J Roentgenol. 2007;189:429–436
  7. De Bazelaire C, Rofsky NM, Duhamel G, Michaelson MD, George D, Alsop DC. Arterial spin labeling blood flow magnetic resonance imaging for the characterization of metastatic renal cell carcinoma. Acad Radiol. 2005;12:347–357
  8. Williams LR, Leggett RW. Reference values for resting blood flow to organs of man. Clin Phys Physiol Meas. 1989;10:187–217
  9. Schramm W, Yang D, Haemmerich D. Contribution of direct heating, thermal conduction and perfusion during radiofrequency and microwave ablation. Conf Proc IEEE Eng Med Biol Soc. 2006;1:5013–5016
  10. Yu NC, Raman SS, Kim YJ, Lassman C, Chang X, Lu DS. Microwave liver ablation: influence of hepatic vein size on heat–sink effect in a porcine model. J Vasc Interv Radiol. 2008;19:1087–1092
  11. Wright AS, Sampson LA, Warner TF, Mahvi DM, Lee FT. Radiofrequency versus microwave ablation in a hepatic porcine model. Radiology. 2005;236:132–139
  12. Brace CL, Laeseke PF, van der Weide DW, Lee FT. Microwave ablation with a triaxial antenna: results in ex vivo bovine liver. IEEE Trans Microw Theory Tech. 2005;53:215–220
  13. Brace CL, Laeseke PF, Sampson LA, Frey TM, van der Weide DW, Lee FT. Microwave ablation with multiple simultaneously powered small–gauge triaxial antennas: results from an in vivo swine liver model. Radiology. 2007;244:151–156
  14. Brace CL, Laeseke PF, Sampson LA, Frey TM, van der Weide DW, Lee FT. Microwave ablation with a single small-gauge triaxial antenna: in vivo porcine liver model. Radiology. 2007;242:435–440
  15. Goldberg SN, Grassi CJ, Cardella JF, et al. Image-guided tumor ablation: standardization of terminology and reporting criteria. J Vasc Interv Radiol. 2005;16:765–778
  16. Institute of Laboratory Animal Resources (U.S.). Guide for the care and use of laboratory animals. In: 7th ed.. Washington, DC: National Academy Press; 1996;
  17. Laeseke PF, Sampson LA, Frey TM, et al. Multiple-electrode radiofrequency ablation: comparison with a conventional cluster electrode in an in vivo porcine kidney model. J Vasc Interv Radiol. 2007;18:1005–1010
  18. Goldberg SN, Stein MC, Gazelle GS, Sheiman RG, Kruskal JB, Clouse ME. Percutaneous radiofrequency tissue ablation: optimization of pulsed-radiofrequency technique to increase coagulation necrosis. J Vasc Interv Radiol. 1999;10:907–916
  19. Durick NA, Laeseke PF, Broderick LS, et al. Microwave ablation with triaxial antennas tuned for lung: results in an in vivo porcine model. Radiology. 2008;247:80–87
  20. Hope WW, Schmelzer TM, Newcomb WL, et al. Guidelines for power and time variables for microwave ablation in an in vivo porcine kidney. J Surg Res. 2009;153:263–267
  21. Clark PE, Woodruff RD, Zagoria RJ, Hall MC. Microwave ablation of renal parenchymal tumors before nephrectomy: phase I study. AJR Am J Roentgenol. 2007;188:1212–1214
  22. Liang P, Wang Y, Zhang D, Yu X, Gao Y, Ni X. Ultrasound guided percutaneous microwave ablation for small renal cancer: initial experience. J Urol. 2008;180:844–848
  23. Gervais DA, Arellano RS, McGovern FJ, McDougal WS, Mueller PR. Radiofrequency ablation of renal cell carcinoma: part 2, lessons learned with ablation of 100 tumors. AJR Am J Roentgenol. 2005;185:72–80

 P.F.L. and C.L.B. have ownership interest in and receive consulting fees from NeuWave Medical (Madison, Wisconsin), which owns the license to the triaxial microwave antenna design described in this study. F.T.L. and D.W.v.d.W. have ownership interest in NeuWave Medical. L.A.S. receives consulting fees from NeuWave Medical.

 This study was funded in part by the National Institutes of Health (Bethesda, Maryland).

PII: S1051-0443(09)00577-6

doi: 10.1016/j.jvir.2009.05.029

Journal of Vascular and Interventional Radiology
Volume 20, Issue 9 , Pages 1224-1229 , September 2009