Journal of Vascular and Interventional Radiology
Volume 21, Issue 3 , Pages 367-374 , March 2010

Toward an Optimal Position for Inferior Vena Cava Filters: Computational Modeling of the Impact of Renal Vein Inflow with Celect and TrapEase Filters

  • Stephen L. Wang, MD

      Affiliations

    • Division of Vascular and Interventional Radiology, Kaiser Permanente Santa Clara Medical Center, Santa Clara, California
    • Corresponding Author InformationAddress correspondence to S.L.W., Division of Vascular and Interventional Radiology, Kaiser Permanente Santa Clara Medical Center, 700 Lawrence Expwy., Santa Clara, CA 95051
  • ,
  • Michael A. Singer, PhD

      Affiliations

    • Center for Applied Scientific Computing, Lawrence Livermore National Laboratory, Livermore, California

Received 16 July 2009 ,Revised 28 October 2009 ,Accepted 11 November 2009.

  • Image Result

    Schematic diagram of the three-dimensional model showing the IVC, renal veins, and filter positions. Letters AF correspond to positions of the downstream cone of the Celect and TrapEase filters. Posi

    Schematic diagram of the three-dimensional model showing the IVC, renal veins, and filter positions. Letters AF correspond to positions of the downstream cone of the Celect and TrapEase filters. Positions A and B are infrarenal, C is just below juxtarenal position with the cone near the level of the renal vein inflow, D and E are juxtarenal, and F is suprarenal in position.

  • Image Result
    Models of the unoccluded TrapEase and Celect filters within the computational model of the IVC and renal veins. Filters are positioned at vena cava positions C and F in the schematic diagram in Figure

    Models of the unoccluded TrapEase and Celect filters within the computational model of the IVC and renal veins. Filters are positioned at vena cava positions C and F in the schematic diagram in Figure 1. Note the regions of naturally occurring stagnant flow (arrows) along the bilateral vena cava walls just downstream of the renal venous inflow.

  • Image Result
    Normalized WSS profiles for the Celect filter in different IVC positions (see A–F in Fig 1) with a 1.0 mL spherical thrombus in the central downstream trapping position. Dotted line indicates Celect f

    Normalized WSS profiles for the Celect filter in different IVC positions (see AF in Fig 1) with a 1.0 mL spherical thrombus in the central downstream trapping position. Dotted line indicates Celect filter at position C without thrombus. Both sides of the vena cava wall are evaluated. Flow is from left to right, and the x-axis denotes the distance (in mm) from the downstream tip of the filter. Symmetry is observed in the Celect filter with low WSSs downstream of the thrombus and relatively high shear stresses with suprarenal placement (position F in Fig 1). Breaks in the WSS lines correspond with the locations of renal vein inflow where no wall is present.

  • Image Result
    Normalized WSS profiles for the TrapEase filter in different IVC positions (see A–F in Fig 1) with a 1.0 mL spherical thrombus in the central downstream trapping position (a) or a 0.5 mL spherical thr

    Normalized WSS profiles for the TrapEase filter in different IVC positions (see AF in Fig 1) with a 1.0 mL spherical thrombus in the central downstream trapping position (a) or a 0.5 mL spherical thrombus in the right lateral upstream trapping position (b). Dotted line indicates TrapEase filter at position C (see Fig 1) without thrombus. Both sides of the vena cava wall are evaluated. Flow is from left to right, and the x-axis denotes distance (in mm) from the downstream tip of the filter. Breaks in the lines of WSS correspond with the locations of renal vein inflow where no wall is present. (a) Symmetry is observed in the TrapEase filter with low WSSs downstream of the thrombus and relatively high shear stresses with suprarenal placement (position F in Fig 1). (b) At position F (red line), there is a decrease in the WSS along the right wall at approximately 50 mm proximal to the downstream tip of the filter, which is a result of the overlap between the stagnant/recirculating flow downstream of the renal vein inflow (from 55 mm to 60 mm upstream of the tip) and the flow disruption caused by the upstream, laterally trapped thrombus.

  • Image Result
    TrapEase filter at IVC positions A, C, and F (see Fig 1) with a 0.5 mL thrombus in the upstream trapping position (A1, C1, and F1) and a 1.0 mL thrombus in the downstream trapping position (A2, C2, an

    TrapEase filter at IVC positions A, C, and F (see Fig 1) with a 0.5 mL thrombus in the upstream trapping position (A1, C1, and F1) and a 1.0 mL thrombus in the downstream trapping position (A2, C2, and F2). Color scale corresponds with normalized velocities. For configurations F1 and F2, the arrows denote regions of naturally occurring stagnant/recirculating flow caused by renal inflow.

  • Image Result
    Flow past the Celect filter partially occluded with a 1.0-cm3 thrombus. The velocity color scale is normalized (to pipe flow), and all images have the same scale. The filters are positioned at IVC sta

    Flow past the Celect filter partially occluded with a 1.0-cm3 thrombus. The velocity color scale is normalized (to pipe flow), and all images have the same scale. The filters are positioned at IVC stations AF (see Fig 1).

 Computer time on the Lawrence Livermore National Laboratory's Yana cluster was provided under Livermore Computing's Multiprogrammatic and Institutional Computing Initiative. The Lawrence Livermore National Laboratory is operated by Lawrence Livermore National Security for the United States Department of Energy, National Nuclear Security Administration, under Contract DEAC5207NA27344.

 Neither author has identified a conflict of interest.

PII: S1051-0443(09)01145-2

doi: 10.1016/j.jvir.2009.11.013

Journal of Vascular and Interventional Radiology
Volume 21, Issue 3 , Pages 367-374 , March 2010