Journal of Vascular and Interventional Radiology
Volume 21, Issue 3 , Pages 348-356 , March 2010

Comparison of Gadoxetic Acid–enhanced MR Imaging versus Four-phase Multi–detector Row Computed Tomography in Assessing Tumor Regression after Radiofrequency Ablation in Subjects with Hepatocellular Carcinomas

  • Jung-Hee Yoon, MD, PhD

      Affiliations

    • Department of Radiology, Busan Paik Hospital, Inje University College of Medicine, Busan, Korea
    • Corresponding Author InformationAddress correspondence to J.H.Y., Department of Radiology, University of California San Diego Medical Center-Hillcrest, 408 Dickinson St., San Diego, CA 92103-8226
  • ,
  • Eun-Joo Lee, MD, PhD

      Affiliations

    • Department of Radiology, Busan Paik Hospital, Inje University College of Medicine, Busan, Korea
  • ,
  • Seong-Sook Cha, MD, PhD

      Affiliations

    • Department of Radiology, Busan Paik Hospital, Inje University College of Medicine, Busan, Korea
  • ,
  • Sang-Suk Han, MD, PhD

      Affiliations

    • Department of Radiology, Busan Paik Hospital, Inje University College of Medicine, Busan, Korea
  • ,
  • Suk-Jin Choi, MD, PhD

      Affiliations

    • Department of Radiology, Busan Paik Hospital, Inje University College of Medicine, Busan, Korea
  • ,
  • Jae-Ryang Juhn, MD, PhD

      Affiliations

    • Department of Radiology, Busan Paik Hospital, Inje University College of Medicine, Busan, Korea
  • ,
  • Myung-Hee Kim, MD

      Affiliations

    • Department of Radiology, Busan Paik Hospital, Inje University College of Medicine, Busan, Korea
  • ,
  • Yeon-Jae Lee, MD, PhD

      Affiliations

    • Department of Internal Medicine, Busan Paik Hospital, Inje University College of Medicine, Busan, Korea
  • ,
  • Seong-Jae Park, MD, PhD

      Affiliations

    • Department of Internal Medicine, Busan Paik Hospital, Inje University College of Medicine, Busan, Korea

Received 6 April 2009 ,Revised 11 November 2009 ,Accepted 16 November 2009.

References 

  1. Dodd GD, Soulen MC, Kane RA, et al. Minimally invasive treatment of malignant hepatic tumors: at the threshold of a major breakthrough. Radiographics. 2000;20:9–27
  2. Vogl TJ, Mack M, Straub R, et al. Percutaneous interstitial thermotherapy of malignant liver tumors. Rofo. 2000;172:12–22
  3. Livraghi T, Goldberg SN, Lazzaroni S, Meloni F, Solbiati L, Gazelle GS. Small hepatocellular carcinoma: treatment with radio-frequency ablation versus ethanol injection. Radiology. 1999;210:655–661
  4. McGahan JP, Dodd GD. Radiofrequency ablation of the liver: current status. AJR Am J Roentgenol. 2001;176:3–16
  5. Goldberg SN, Gazelle GS, Mueller PR. Thermal ablation therapy for focal malignancy: a unified approach to underlying principles, techniques, and diagnostic imaging guidance. AJR Am J Roentgenol. 2000;174:323–331
  6. Solbiati L, Ierace T, Goldberg SN, et al. Percutaneous US-guided radio-frequency tissue ablation of liver metastases: treatment and follow-up in 16 patients. Radiology. 1997;202:195–203
  7. Solbiati L, Goldberg SN, Ierace T, et al. Hepatic metastases: percutaneous radio-frequency ablation with cooled-tip electrodes. Radiology. 1997;205:367–373
  8. Lim HK, Han JK. Hepatocellular carcinoma: evaluation of therapeutic response to interventional procedures. Abdom Imaging. 2002;27:168–179
  9. Khankan AA, Murakami T, Onishi H, et al. Hepatocellular carcinoma treated with Radiofrequency ablation: an early evaluation with Magnetic resonance imaging. J Magn Reso Imaging. 2008;27:546–551
  10. Onishi H, Matsushita M, Murakami T, et al. MR appearances of radiofrequency thermal ablation region: histopathologic correlation with dog liver models and an autopsy case. Acad Radiol. 2004;11:1180–1189
  11. Lencioni R, Caramella D, Bartolozzi C. Response of hepatocellular carcinoma to percutaneous ethanol injection: CT and MR evaluation. J Comput Assist Tomogr. 1993;17:723–729
  12. Sironi S, Livraghi T, Meloni F, De Cobelli F, Ferrero C, Del Maschio A. Small hepatocellular carcinoma treated with percutaneous RF ablation: MR imaging follow-up. AJR Am J Roentgenol. 1999;173:1225–1229
  13. Dromain C, De Baere T, Elias D, et al. Hepatic tumors treated with percutaneous radio-frequency ablation: CT and MR imaging follow-up. Radiology. 2002;223:255–262
  14. Huppertz A, Haraida S, Kraus A, et al. Enhancement of focal liver lesions at gadoxetic acid-enhanced MR imaging: correlation with histopathologic findings and spiral CT—initial observations. Radiology. 2005;234:468–478
  15. Reimer P, Rummeny EJ, Daldrup HE, et al. Enhancement characteristics of liver metastases, hepatocellular carcinomas, and hemangiomas with Gd-EOB-DTPA: preliminary results with dynamic MR imaging. Eur Radiol. 1997;7:275–280
  16. Reimer P, Schneider G, Schima W. Hepatobiliary contrast agents for contrast-enhanced MRI of the liver: properties, clinical development and applications. Eur Radiol. 2004;14:559–578
  17. Llovet JM, Di Bisceglie AM, Bruix J, et al. Design and endpoints of clinical trials in hepatocellular carcinoma. J Natl Cancer Inst. 2008;100:698–711
  18. Lim KO, Stark DD, Leese PT, Pfefferbaum A, Rocklage SM, Quay SC. Hepatobiliary MR imaging: first human experience with MnDPDP. Radiology. 1991;178:79–82
  19. Wile GE, Leyendecker JR, Krehbiel KA, Dyer RB, Zagoria RJ. CT and MR imaging after imaging-guided thermal ablation of renal neoplasms. Radiographics. 2007;27:325–339
  20. Merkle EM, Nour SG, Lewin JS. MR imaging follow-up after percutaneous radiofrequency ablation of renal cell carcinoma: findings in 18 patients during first 6 months. Radiology. 2005;235:1065–1071
  21. Remer EM, Weinberg EJ, Oto A, et al. MR imaging of the kidneys after laparoscopic cryoablation. AJR Am J Roentgenol. 2000;174:635–640
  22. Svatek RS, Sims R, Anderson JK, et al. Magnetic resonance imaging characteristics of renal tumors after radiofrequency ablation. Urology. 2006;67:508–512
  23. Matsumoto ED, Watumull L, Johnson DB, et al. The radiographic evolution of radio frequency ablated renal tumors. J Urol. 2004;172:45–48
  24. Bolte SL, Ankem MK, Moon TD, et al. Magnetic resonance imaging findings after laparoscopic renal cryoablation. Urology. 2006;67:485–489
  25. Lee JD, Lee JM, Kim SW, Kim CS, Mun WS. MR imaging-histopathologic correlation of radiofrequency thermal ablation lesion in a rabbit liver model: observation during acute and chronic stages. Korean J Radiol. 2001;2:151–158
  26. Brewer WH, Austin RS, Capps GW, et al. Intraoperative monitoring and postoperative imaging of hepatic cryosurgery. Semin Surg Oncol. 1998;14:129–155
  27. Erce C, Parks RW. Interstitial ablative techniques for hepatic tumors. Br J Surg. 2003;90:272–289
  28. Kuszyk BS, Boitnott JK, Choti MA, et al. Local tumor recurrence following hepatic cryoablation: radiologic-histopathologic correlation in a rabbit model. Radiology. 2000;217:477–486
  29. Tsuda M, Rikimaru H, Majima K, et al. Time-related changes of radiofrequency ablation lesion in the normal rabbit liver: finding of magnetic resonance imaging and histopathology. Invest Radiol. 2003;38:525–531
  30. Rhim H, Yoon KH, Lee JM, et al. Major complications after radio-frequency thermal ablation of hepatic tumors: spectrum of imaging findings. Radiographics. 2003;23:123–134
  31. Lim HK, Choi D, Lee WJ, et al. Hepatocellular carcinoma treated with percutaneous radio-frequency ablation: evaluation with follow-up multiphase helical CT. Radiology. 2001;221:447–454

 This work was supported by the 2003 Inje University Research Grant. Support for manuscript editing was received from Bayer Korea. None of the authors have identified a conflict of interest.

 From the SIR 2009 Annual Meeting.

PII: S1051-0443(09)01146-4

doi: 10.1016/j.jvir.2009.11.014

Journal of Vascular and Interventional Radiology
Volume 21, Issue 3 , Pages 348-356 , March 2010